A NEW AREA OF PLANT BREEDING

AI powered production of Doubled Haploid plants to enable novel traits

Our Motivation

Increasing changes in the global food market (e.g. population growth to rise by 60% through 2050, climate change calling for 70% higher productivity due to harvest losses by insects, pathogens, weeds and other limited resources like water) cause major challenges for the plant breeding industry.

The traditional plant breeding process is too slow to cope with these global changes, whilst confronting the needs to provide crops with improved characteristics faster and cheaper, accelerate genetic gain and generate homogenous plants in shorter time and lower costs.

Plant breeders face literally millions of choices when developing a new variety. Today, it takes many years of painstaking breeding to tweak superior traits by serendipity until it is just right for sustainable agriculture. Genetically pure starting material is of key importance for breeders to get faster access to genetic resources to increase productivity of new cultivars. As a growing population and climate change threaten food supply and security, innovative solutions are needed to facilitate breeding precision and output and lessen the impact of agriculture on the environment.

Doubled Haploid plants enabled by digital technology can solve major obstacles plant breeders are facing today

The generation of Doubled Haploid plants speeds up the breeding process and increases the genetic gain (access to genetic resources for generating better varieties). Unfortunately, with currently available techniques, most of agriculturally important plants are recalcitrant to the formation of the Doubled Haploid plants. Enabling Doubled Haploid technology means faster time to market and more efficient use of resources, since fewer plants are required to find the desired genetic traits.

Our Mission

ScreenSYS mission is to make Doubled Haploid plants widely available for breeders with our novel technology platform utilizing state-of-the-art algorithms, chemical inducers and automated cell handling.

We apply our know-how and innovative solutions to enable in vitro reprogramming of microspores, precursor cells of pollen, with subsequent generation of Doubled Haploid plants from these haploid cells.

ScreenSYS industrializes Doubled Haploid plant generation with its unique AI-powered automated platform based workflow. ScreenSYS is the first plant biotechnology digital in vitro company that generates Doubled Haploid plants by utilizing algorithms and patented cell handling expertise to measure embryogenic competence of microspores and guide their reprogramming in vitro. Our innovative highly automated workflow offers the fastest and the most efficient route to boost production of homozygous inbred lines and broadly applicable to other single plant cells, such as protoplasts. With our technology breeders will benefit on their challenging quest to find and access superior traits quicker and cheaper, be it improved use of water or nutrients, adaptation to climate change, or resistance against pathogens and diseases.

ScreenSYS breaks recalcitrance, enables development of plant embryos and makes Doubled Haploid plants broadly available.

ScreenSYS empowers plant breeders with disruptive technology for Doubled Haploid plant production – breaking recalcitrance in relevant plants

What we do

We are an interdisciplinary team of machine learners, image analysts, data scientists, plant biology and tissue culture experts, robotics and software engineers, and business professionals dedicated to offer AI from our research lab to the needs of plant breeders world.

What we offer

Partnered Discovery:
R&D Projects with Plant Breeders

We support you by breaking recalcitrance in your desired target plant species or variety to enable your favoured Doubled Haploid breeding material

Improve plant in vitro culture with the help of cutting edge AI algorithms and automated assays by learning from millions of cultured cells at the best microscopy resolution

Identify chemicals regu­lating essential cellular processes to trigger embryo and Doubled Haploid plant development in your favoured plant species

Apply state-of-the-art algorithms to combine single chemicals to over­come recalcitrance and enable geno­type indepen­dent Doubled Haploid plant production

INTERESTED TO LEARN, WHETHER SCREENSYS TECHNOLOGY IS READY FOR YOUR CROP?

Please send us your floral samples and we come up with our offer after a charge-free pilot test.

Production of Doubled Haploid plants with breeders as clients

All you need to take care of is to provide us your “donor” plant material or seeds

We will take care of solutions to  enable the Doubled Haploid plant production

Production facility for selected crops is planned to be open soon

Contact us

Postal address
ScreenSYS GmbH
BioTechPark
Engesserstraße 4A
79108 Freiburg
Germany

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In the News

ScreenSYS discovers specific chemical regulators that reprogram individual plant cells to divide and develop. However, no two plant species are the same, and new species often present new challenges in terms of controlling the reprogramming of their cells.
16.05.2023

New breeding methods for grapevines

Since October 2022, ScreenSYS has been a partner in the EU-funded Interregio project “Climate-Resilient Grape Varieties to Secure Yields” (in short “Kliwiresse” from the German title “Klima-Widerstandsfähige Rebsorten zur Sicherung des Ertrags”).
2019 | Nature Methods

U-Net: deep learning for cell counting, detection, and morphometry

Volume: 16 (Isssue: 1), Pages: 67-+ DOI: 10.1038/s41592-018-0261-2
2016 | BMC Plant Biology

A detailed expression map of PIN1 auxin transporter in Arabidopsis thaliana root.

Career

Meet the team

Multidisciplinary team with diverse skill sets:

Doubled Haploid Technology

Engineering and Process Automation

High content and high throughput MICROSCOPY

Assay Development

AI and Machine Learning

Data Analytics

CHEMICAL GENETICS

In Vitro Plant Production

Business Development

ScreenSYS Team 2020

Oleksandr Dovzhenko

CEO/COO and shareholder

  • Experience in team management and organization of research facilities
  • >20 years plant research experience with strong background in scientific and technological areas
  • Inventor of automated single plant cell handling for cell tracking and predictive phenotyping in plant cell cultures
  • Proven success in developing innovative concepts, leading and coordinating projects and attracting public funds

Klaus Palme

CSO/CHRO and shareholder

  • 30 years plant research experience
  • Proven expertise in plant signalling, molecular biology, genetics and systems biology by more than 240 publications
  • Elected member in several scientific societies, awarded with many scientific prices
  • Scientific director of numerous successful large scale projects

Klaus Nitschke

Senior Advisor Strategy Development, Fund Raising and shareholder

  • PhD Max Planck Institute for Plant Breeding, Cologne
  • Partner/Shareholder McKinsey spin off consultancy trade sale to Deloitte Consulting
  • COO BOL, Bertelsmann
  • MD Digital Innovation Factory and Chief Strategist for German and European Business, Deutsche Telekom
  • MD/Partner, Boston Consulting Group Digital Ventures
  • Director Berlin Health Innovations and Senior Advisor Digital Health, Berlin Institute of Health (BIH), Charite
  • Seed Investor in 4 start ups